HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Bromofuran-2-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Bromofuran-2-carboxylic acid | HCID 605479 | — |
| Product | 3-Bromofuran-2-carbonyl chloride | HCID 21864576 | — |
Reaction Steps
Compounds of this invention with Formulae I-IX may be prepared as illustrated by the exemplary reaction in Scheme 2. Reaction of 3-bromo-furan-2-carboxylic acid with thionyl chloride produces intermediate, 3-bromo-furan-2-carbonyl chloride, followed by refluxing with 4-trifluoromethyl-benzamidoxime in pyridine produces the product 5-(3-bromo-furan)-3-(4-trifluoromethyl-phenyl)-[1,2,4]-oxadiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435750B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-209a46d3a39a4c428b257bbcc119fb2d |
| Source note | uspto-grants-2008_10 |