Methylhydrazine → HCID 22147906, compound

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Reaction Steps

5-(4-Chloro-phenyl)-3-(3-chloro-thiophen-2-yl)-1-methyl-4,5-dihydro-1H-pyrazole: The title compound was prepared from 3-(4-chloro-phenyl)-1-(3-chloro-thiophen-2-yl)-propenone (50 mg, 0.176 mmol) and methylhydrazine (9 μL, 0.17 mmol) by a procedure similar to Example 105a as a yellowish oil (20.9 mg, 38%). 1H NMR (CDCl3): 7.24 (m, 4H), 7.09 (d, J=6.6 Hz, 1H), 6.75 (d, J=6.60 Hz, 1H), 4.08 (m, 1H), 3.83 (m, 1H), 2.98 (t, 1H), 2.67 (s, 3H).

Provenance & Evidence