HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-2,3-dihydro-1,3-benzoxazol-2-one → HCID 69100474, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-2,3-dihydro-1,3-benzoxazol-2-one | HCID 26856 | — |
| Reactant | [4-(4-Fluorobenzyl)piperidin-1-yl](oxo)acetic acid | HCID 51342220 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 69100474 | HCID 69100474 | — |
Reaction Steps
The title compound is prepared from 5-amino-3H-benzoxazol-2-one [J. Med. Chem., 10, 408. (1967)] and [4-(4-fluoro-benzyl)-piperidin-1-yl]-oxo-acetic acid (Example 1b) according to the method described in Example 2. Melting Point: 226-231° C. (water)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-8b6fb5b05fd24801bfa5f1fcd184570e |
| Source note | uspto-grants-2008_10 |