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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2114965Generated: October 31, 2026

4-Aminobenzonitrile → N-(4-Cyanophenyl)-α-oxo-4-(phenylmethyl)-1-piperidineacetamide

https://huagongshe.com/reaction/2114965

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminobenzonitrileHCID 13396—
Reactant(4-Benzylpiperidin-1-yl)oxoacetic acidHCID 16110264—
SolventDiethyl EtherHCID 3283—
ProductN-(4-Cyanophenyl)-α-oxo-4-(phenylmethyl)-1-piperidineacetamideHCID 69100690—

Reaction Steps

The title compound is prepared from 4-amino-benzonitrile (Aldrich) and (4-benzyl-piperidin-1-yl)-oxo-acetic acid according to the method described in Example 2. Melting Point: 166-169° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-18171380dadf4ca5ac780b4655988f4e
Source noteuspto-grants-2008_10