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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2114973Generated: October 26, 2026

3-Aminobenzonitrile → N-(3-Cyano-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl)-2-oxo-acetamide

https://huagongshe.com/reaction/2114973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AminobenzonitrileHCID 16702—
Reactant[4-(4-Fluorobenzyl)piperidin-1-yl](oxo)acetic acidHCID 51342220—
SolventDiethyl EtherHCID 3283—
ProductN-(3-Cyano-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl)-2-oxo-acetamideHCID 69100240—

Reaction Steps

The title compound is prepared from [4-(4-fluoro-benzyl)-piperidin-1-yl]-oxo-acetic acid (Example 1b) and 3-aminobenzonitrile (Aldrich) according to the method described in Example 1c. Melting Point: 135-138° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-056c94fc2e1c47b094430ba863a0e9a4
Source noteuspto-grants-2008_10