4-Aminophenol → HCID 10290921, compound

HRID 2114976Notes

Reaction equation

HRID 2114976 reaction equation
[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:18])[C:15]([OH:17])=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:19][C:20]1[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=1>C(OCC)C>[CH2:1]([CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:18])[C:15]([NH:19][C:20]2[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=2)=[O:17])[CH2:12][CH2:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 4034-AminophenolHCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acid

Product 1

HCID 10290921HCID 10290921, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) and 4-aminophenol (Aldrich) according to the method described in Example 1c. Melting Point: 167-169° C. (diethylether).

Sources & evidence

ORD record
ord-3ec9206581c04042ade167ca84abb0cd
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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