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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2114977Generated: October 25, 2026

4-(Methylsulfonamido)aniline → 2-(4-Benzyl-piperidin-1-yl)-N-(4-methanesulfonylamino-phenyl)-2-oxo-acetamide

https://huagongshe.com/reaction/2114977

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylsulfonamido)anilineHCID 3732577—
Reactant(4-Benzylpiperidin-1-yl)oxoacetic acidHCID 16110264—
SolventWaterHCID 962—
Product2-(4-Benzyl-piperidin-1-yl)-N-(4-methanesulfonylamino-phenyl)-2-oxo-acetamideHCID 10273323—

Reaction Steps

The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) and N-(4-amino-phenyl)-methanesulfonamide [Tetrahedron, 42, 5739. (1986)] according to the method described in Example 2. Melting Point: 221-225° C. (water)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-fe52e375ec2e4ce183a9bb892ca26157
Source noteuspto-grants-2008_10