4-[(4-Methylphenyl)methyl]piperidine → 2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamide

HRID 2115022노트

반응식

HRID 2115022 반응식
[O:1]=[C:2]1[NH:6][C:5]2[CH:7]=[CH:8][C:9]([NH:11][C:12](=[O:16])[C:13]([OH:15])=O)=[CH:10][C:4]=2[S:3]1.[CH3:17][C:18]1[CH:30]=[CH:29][C:21]([CH2:22][CH:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)=[CH:20][CH:19]=1>C(OCC)C>[CH3:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:22][CH:23]2[CH2:28][CH2:27][N:26]([C:13](=[O:15])[C:12]([NH:11][C:9]3[CH:8]=[CH:7][C:5]4[NH:6][C:2](=[O:1])[S:3][C:4]=4[CH:10]=3)=[O:16])[CH2:25][CH2:24]2)=[CH:29][CH:30]=1

참가 물질

4

반응물 2

HCID 33756034-[(4-Methylphenyl)methyl]piperidineHCID 53306726N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acid

생성물 1

HCID 102729312-[4-(4-Methyl-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamide

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

The title compound is prepared from N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acid (Example 61b) and 4-(4-methyl-benzyl)-piperidine according to the method described in Example 1c. Melting Point: 221-222° C. (diethylether)

출처 및 근거

ORD 기록
ord-8e2f6f1820da4237af438e017f1755d7
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435744B2

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