HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(4-Methylphenyl)methyl]piperidine → 2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(4-Methylphenyl)methyl]piperidine | HCID 3375603 | — |
| Reactant | N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acid | HCID 53306726 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamide | HCID 10272931 | — |
Reaction Steps
The title compound is prepared from N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acid (Example 61b) and 4-(4-methyl-benzyl)-piperidine according to the method described in Example 1c. Melting Point: 221-222° C. (diethylether)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-8e2f6f1820da4237af438e017f1755d7 |
| Source note | uspto-grants-2008_10 |