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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115023Generated: October 26, 2026

Diethyl Ether → 2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamide

https://huagongshe.com/reaction/2115023

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
Reactant4-(4-Chlorobenzyl)piperidineHCID 3732780—
ReactantN-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acidHCID 53306726—
Product2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamideHCID 10137641—

Reaction Steps

The title compound is prepared from N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acid (Example 61b) and 4-(4-chloro-benzyl)-piperidine according to the method described in Example 1c. Melting Point: 245-247° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-33c6d3f6510246638d6eb0a8d01b748f
Source noteuspto-grants-2008_10