4-(4-Methylphenoxy)piperidine → N-(2-Mercapto-3H-benzimidazol-5-yl)-2-(4-p-tolyloxy-piperidin-1-yl)-2-oxo-acetamide

HRID 2115024Notes

Reaction equation

HRID 2115024 reaction equation
[SH:1][C:2]1[NH:3][C:4]2[CH:10]=[C:9]([NH:11][C:12](=[O:16])[C:13]([OH:15])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.[C:17]1([CH3:30])[CH:22]=[CH:21][C:20]([O:23][CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)=[CH:19][CH:18]=1>C(OCC)C>[SH:1][C:2]1[NH:3][C:4]2[CH:10]=[C:9]([NH:11][C:12](=[O:16])[C:13]([N:27]3[CH2:28][CH2:29][CH:24]([O:23][C:20]4[CH:21]=[CH:22][C:17]([CH3:30])=[CH:18][CH:19]=4)[CH2:25][CH2:26]3)=[O:15])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 2

HCID 38374974-(4-Methylphenoxy)piperidineHCID 178526016Oxo[(2-sulfanylidene-2,3-dihydro-1H-benzimidazol-5-yl)amino]acetic acid

Product 1

HCID 178426789N-(2-Mercapto-3H-benzimidazol-5-yl)-2-(4-p-tolyloxy-piperidin-1-yl)-2-oxo-acetamide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from N-(2-mercapto-3H-benzimidazol-5-yl)-oxalamic acid (Example 60b) and 4-p-tolyloxy-piperidine according to the method described in Example 1c. Melting Point: 311-314° C. (diethylether)

Sources & evidence

ORD record
ord-044f03961fbb4026a04fa3caef4d30ce
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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