N-(tert-butoxycarbonyl)glycine → HCID 69099965, compound

HRID 2115026Notes

Reaction equation

HRID 2115026 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([NH:8][C:9](=[O:25])[C:10]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:14][CH2:13]2)=[O:11])[CH:5]=[CH:6][CH:7]=1.[C:26]([O:30][C:31]([NH:33][CH2:34][C:35](O)=[O:36])=[O:32])([CH3:29])([CH3:28])[CH3:27]>C(OCC)C>[C:26]([O:30][C:31](=[O:32])[NH:33][CH2:34][C:35](=[O:36])[NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([NH:8][C:9](=[O:25])[C:10]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH2:14][CH2:13]2)=[O:11])[CH:3]=1)([CH3:29])([CH3:27])[CH3:28]

Participants

4

Reactant 2

HCID 78288N-(tert-butoxycarbonyl)glycineHCID 69100250HCID 69100250, compound

Product 1

HCID 69099965HCID 69099965, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from N-(3-aminophenyl)-2-(4-benzyl-piperidin-1-yl)-2-oxo-acetamide (Example 11) and N-(tert-butoxycarbonyl)glycine (Aldrich) according to the method described in Example 1c. Melting Point: 81-85° C. (diethylether)

Sources & evidence

ORD record
ord-df1948840be749b6b80c069f8bd5a827
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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