2-Aminobenzonitrile → HCID 69100638, compound

HRID 2115033Notes

Reaction equation

HRID 2115033 reaction equation
[F:1][C:2]1[CH:19]=[CH:18][C:5]([CH2:6][CH:7]2[CH2:12][CH2:11][N:10]([C:13](=[O:17])[C:14]([OH:16])=O)[CH2:9][CH2:8]2)=[CH:4][CH:3]=1.[NH2:20][C:21]1[CH:28]=[CH:27][CH:26]=[CH:25][C:22]=1[C:23]#[N:24]>C(OCC)C>[C:23]([C:22]1[CH:25]=[CH:26][CH:27]=[CH:28][C:21]=1[NH:20][C:14](=[O:16])[C:13]([N:10]1[CH2:9][CH2:8][CH:7]([CH2:6][C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:19][CH:18]=2)[CH2:12][CH2:11]1)=[O:17])#[N:24]

Participants

4

Reactant 2

HCID 729132-AminobenzonitrileHCID 51342220[4-(4-Fluorobenzyl)piperidin-1-yl](oxo)acetic acid

Product 1

HCID 69100638HCID 69100638, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from [4-(4-fluoro-benzyl)-piperidin-1-yl]-oxo-acetic acid (Example 1b) and 2-amino-benzonitrile (Aldrich) according to the method described in Example 1c. Melting Point: 101-103° C. (diethylether)

Sources & evidence

ORD record
ord-180de7900b0c4d13877c2ca0c7fcc301
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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