Benzaldehyde → HCID 69100099, compound

HRID 2115051Notes

Reaction equation

HRID 2115051 reaction equation
Cl.[NH2:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10](=[O:26])[C:11]([N:13]2[CH2:18][CH2:17][CH:16]([CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH2:15][CH2:14]2)=[O:12])=[CH:5][CH:4]=1.[CH:27](=O)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>C(OCC)C>[CH2:27]([NH:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10](=[O:26])[C:11]([N:13]2[CH2:18][CH2:17][CH:16]([CH2:19][C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH2:15][CH2:14]2)=[O:12])=[CH:5][CH:4]=1)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 69100507HCID 69100507, compound

Product 1

HCID 69100099HCID 69100099, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from N-(4-amino-phenyl)-2-(4-benzyl-piperidin-1-yl)-2-oxo-acetamide hydrochloride (Example 73) and benzaldehyde (Aldrich) according to the method described in Example 91. Melting Point: 126-128° C. (diethylether)

Sources & evidence

ORD record
ord-eb6461aa17ac482a94e9703a2634a02f
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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