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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115056Generated: October 26, 2026

1-Methyl-4-phenoxypiperidine → 2-Oxo-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-2-(4-phenoxymethyl-piperidin-1-yl)-acetamide

https://huagongshe.com/reaction/2115056

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-4-phenoxypiperidineHCID 18722998—
ReactantN-(2-oxo-2,3-dihydro-1H-indol-5-yl)-oxalamic acidHCID 53306725—
SolventDiethyl EtherHCID 3283—
Product2-Oxo-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-2-(4-phenoxymethyl-piperidin-1-yl)-acetamideHCID 69100717—

Reaction Steps

The title compound is prepared from N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-oxalamic acid (Example 101b) and 4-phenoxy-methyl-piperidine according to the method described in Example 1c. Melting Point: 200-202° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-4b7438d3a02e4b0e825e243fbf3c2024
Source noteuspto-grants-2008_10