HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-((4-Methoxyphenyl)methyl)piperidine → 2-{4-[(4-Methoxyphenyl)methyl]piperidin-1-yl}-2-oxo-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-((4-Methoxyphenyl)methyl)piperidine | HCID 3732740 | — |
| Reactant | N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-oxalamic acid | HCID 53306725 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-{4-[(4-Methoxyphenyl)methyl]piperidin-1-yl}-2-oxo-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)acetamide | HCID 69100467 | — |
Reaction Steps
The title compound is prepared from N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-oxalamic acid (Example 101b) and 4-(4-methoxy-benzyl)-piperidine [U.S. Pat. No. 3,632,767 (1972)] according to the method described in Example 1c. Melting Point: 215-217° C. (diethylether)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-678d1c6706b649d0bf2cc0bc0bf50c29 |
| Source note | uspto-grants-2008_10 |