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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115061Generated: October 27, 2026

Diisopropyl Ether → 2-[4-[4-Methoxy-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide

https://huagongshe.com/reaction/2115061

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropyl EtherHCID 7914—
Reactant4-((4-Methoxyphenyl)methyl)piperidineHCID 3732740—
ReactantN-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-oxalamic acidHCID 53306576—
Product2-[4-[4-Methoxy-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamideHCID 10223212—

Reaction Steps

The title compound is prepared from N-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-oxalamic acid (Example 43e) and 4-(4-methoxy-benzyl)-piperidine according to the method described in Example 1c. Melting Point: 193-197° C. (diisopropylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-cb1e682102264ce19eee7237ded5d3c4
Source noteuspto-grants-2008_10