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4-[(4-Fluorophenyl)methyl]piperidine hydrochloride → 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-[(4-Fluorophenyl)methyl]piperidine hydrochloride | HCID 17039492 | — |
| 反応物 | HCID 53310272 | HCID 53310272 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)-acetamide | HCID 69100755 | — |
反応手順
The title compound is prepared from 2-chloro-N-(2-oxo-2,3-dihydro-1H-indol-5-yl)acetamide (Example 143a) and 4-(4-fluoro-benzyl)-piperidine hydrochloride according to the method described in Example 142b. Melting Point: 178-180° C. (diethylether)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07435744B2 |
| 出典データセット | uspto-grants-2008_10 |
| ORD ID | ord-ec0c7b7634194388aad55571ddeb28cc |
| 出典メモ | uspto-grants-2008_10 |