HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzylpiperidine → 2-(4-Benzyl-piperidin-1-yl)-N-(4-cyano-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzylpiperidine | HCID 31738 | — |
| Reactant | 2-chloro-N-(4-cyanophenyl)acetamide | HCID 2168015 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-(4-Benzyl-piperidin-1-yl)-N-(4-cyano-phenyl)-acetamide | HCID 2399822 | — |
Reaction Steps
The title compound is prepared from 2-chloro-N-(4-cyano-phenyl)-acetamide [J. Org. Chem., 23, 141. (1958)] and 4-benzyl-piperidine according to the method described in Example 142b. Melting Point: 120-124° C. (diethylether)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-99df957614d346798c30844297576b93 |
| Source note | uspto-grants-2008_10 |