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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115080Generated: October 25, 2026

4-(4-Fluoro-benzyl)-piperidine → 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(1H-indazol-5-yl)-acetamide

https://huagongshe.com/reaction/2115080

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Fluoro-benzyl)-piperidineHCID 3699841—
Reactant2-chloro-N-(1H-indazol-5-yl)acetamideHCID 17164463—
SolventDiethyl EtherHCID 3283—
Product2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(1H-indazol-5-yl)-acetamideHCID 69100657—

Reaction Steps

The title compound is prepared from 2-chloro-N-(1H-indazol-5-yl)-acetamide (Example 147a) and 4-(4-fluoro-benzyl)-piperidine according to the method described in Example 142b. Melting Point: 149-152° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-9eea7a3a6b3f4a14bfd99619a51fa6f1
Source noteuspto-grants-2008_10