4-(4-Fluoro-benzyl)-piperidine → 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamide

Participants

Role	Name	HCID	Charge
Reactant	4-(4-Fluoro-benzyl)-piperidine	HCID 3699841	—
Reactant	2-chloro-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamide	HCID 24298282	—
Solvent	Diethyl Ether	HCID 3283	—
Product	2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamide	HCID 69100291	—

Reaction Steps

The title compound is prepared from 2-chloro-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamide (Example 153a) and 4-(4-fluoro-benzyl)-piperidine according to the method described in Example 142b. Melting Point: 209-211° C. (diethylether)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07435744B2
Source dataset	uspto-grants-2008_10
ORD ID	ord-68f389801e9649e7a9106d53daeda47f
Source note	uspto-grants-2008_10