6-Amino-1,3-benzoxazole-2(3H)-thione → HCID 86593931, compound

HRID 2115096Notes

Reaction equation

HRID 2115096 reaction equation
Cl.[CH2:2]([CH:9]1[CH2:14][CH2:13][N:12]([CH2:15][C:16]([OH:18])=O)[CH2:11][CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[NH2:19][C:20]1[CH:29]=[CH:28][C:23]2[NH:24][C:25](=[S:27])[O:26][C:22]=2[CH:21]=1>C(O)(C)C>[CH2:2]([CH:9]1[CH2:10][CH2:11][N:12]([CH2:15][C:16]([NH:19][C:20]2[CH:29]=[CH:28][C:23]3[NH:24][C:25](=[S:27])[O:26][C:22]=3[CH:21]=2)=[O:18])[CH2:13][CH2:14]1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 136273456-Amino-1,3-benzoxazole-2(3H)-thioneHCID 67009858HCID 67009858, compound

Product 1

HCID 86593931HCID 86593931, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

The title compound is prepared from (4-benzyl-piperidin-1-yl)-acetic acid hydrochloride and 6-amino-3H-benzoxazole-2-thione according to the method described in Example 161c. Melting Point: 183-184° C. (isopropanol)

Sources & evidence

ORD record
ord-5dfc24ccb582437f81ad5d48002bd77d
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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