Diisopropyl Ether → HCID 69099967, compound

HRID 2115099Notes

Reaction equation

HRID 2115099 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]#[N:13])[CH:7]=1)=[O:4].Cl.[F:15][C:16]1[CH:28]=[CH:27][C:19]([CH2:20][CH:21]2[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]2)=[CH:18][CH:17]=1.C(OC(C)C)(C)C>>[C:12]([C:8]1[CH:7]=[C:6]([NH:5][C:3](=[O:4])[CH2:2][N:24]2[CH2:25][CH2:26][CH:21]([CH2:20][C:19]3[CH:18]=[CH:17][C:16]([F:15])=[CH:28][CH:27]=3)[CH2:22][CH2:23]2)[CH:11]=[CH:10][CH:9]=1)#[N:13]

Participants

4

Reactant 3

HCID 7914Diisopropyl EtherHCID 7357672-chloro-N-(3-cyanophenyl)acetamideHCID 170394924-[(4-Fluorophenyl)methyl]piperidine hydrochloride

Product 1

HCID 69099967HCID 69099967, compound

Procedure

The title compound is prepared from 2-chloro-N-(3-cyano-phenyl)-acetamide (Example 166a) and 4-(4-fluoro-benzyl)-piperidine hydrochloride according to the method described in Example 142b. Melting Point: 101-103° C. (diisopropylether)

Sources & evidence

ORD record
ord-1e192582215a473a8963fc291f484a7d
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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