Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115105Generated: October 30, 2026

Diethyl Ether → 1-Piperidineacetamide,4-[(4-fluorophenyl)methyl]-n-(3-nitrophenyl)-

https://huagongshe.com/reaction/2115105

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
Reactant2-chloro-N-(3-nitrophenyl)acetamideHCID 532066—
Reactant4-Fluoro-benzyl-piperidine hydrochlorideHCID 22557457—
Product1-Piperidineacetamide,4-[(4-fluorophenyl)methyl]-n-(3-nitrophenyl)-HCID 69100357—

Reaction Steps

The title compound is prepared from 2-chloro-N-(3-nitrophenyl)-acetamide and 4-(4-fluoro-benzyl-piperidine hydrochloride according to the method described in Example 142b. Melting Point: 118-120° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-60935b6c69194d75ac8c89d566fe79f9
Source noteuspto-grants-2008_10