HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(4-Fluorophenyl)methyl]piperidine hydrochloride → 1-Piperidineacetamide,4-[(4-fluorophenyl)methyl]-n-[4-[(methylsulfonyl)amino]phenyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(4-Fluorophenyl)methyl]piperidine hydrochloride | HCID 17039492 | — |
| Reactant | 2-chloro-N-[4-(methanesulfonamido)phenyl]acetamide | HCID 43347089 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 1-Piperidineacetamide,4-[(4-fluorophenyl)methyl]-n-[4-[(methylsulfonyl)amino]phenyl]- | HCID 69100556 | — |
Reaction Steps
The title compound is prepared from 2-chloro-N-(4-methanesulfonylamino-phenyl)-acetamide (Example 180a) and 4-(4-fluoro-benzyl)-piperidine hydrochloride according to the method described in Example 142b. Melting Point: 169-171° C. (hexane)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-ecc6ae2e948a4e7e928058c1da64fada |
| Source note | uspto-grants-2008_10 |