HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methyl-p-tolyl-amino)-piperidine → 1-Piperidineacetamide,4-[methyl(4-methylphenyl)amino]-n-[4-[(methylsulfonyl)amino]phenyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methyl-p-tolyl-amino)-piperidine | HCID 61981015 | — |
| Reactant | 1-Piperidineacetamide,n-[4-[(methylsulfonyl)amino]phenyl]-4-(phenylmethyl)- | HCID 69099975 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Piperidineacetamide,4-[methyl(4-methylphenyl)amino]-n-[4-[(methylsulfonyl)amino]phenyl]- | HCID 69101010 | — |
Reaction Steps
The title compound is prepared from 2-chloro-N-(4-methanesulfonylamino-phenyl)-acetamide (Example 180) and 4-(methyl-p-tolyl-amino)-piperidine [Arzneimittel Forschung/Drug Research 44(II), 989. (19994)]) according to the method described in Example 142b. Melting Point: 128-130° C. (diethylether)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-92ad52f871c54b6499ca851957b17b87 |
| Source note | uspto-grants-2008_10 |