Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115113Generated: October 28, 2026

Benzaldehyde → 4-[(4-Fluorophenyl)methyl]-N-[3-[(phenylmethyl)amino]phenyl]-1-piperidineacetamide

https://huagongshe.com/reaction/2115113

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantHCID 69100145HCID 69100145—
SolventDiethylether hexaneHCID 21584099—
Product4-[(4-Fluorophenyl)methyl]-N-[3-[(phenylmethyl)amino]phenyl]-1-piperidineacetamideHCID 69100484—

Reaction Steps

The title compound is prepared from N-(3-amino-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-acetamid dihydrochloride (Example 183) and benzaldehyde according to the method described in Example 177. Melting Point: 98-100° C. (diethylether-hexane)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-f9e414d369634b539b2dee4fc632a0f0
Source noteuspto-grants-2008_10