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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115122Generated: October 30, 2026

1H-Indazol-5-amine → 1-(4-Benzyl-piperidin-1-yl)-2-(1H-indazol-5-yl-amino)-ethanone

https://huagongshe.com/reaction/2115122

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indazol-5-amineHCID 88012—
Reactant1-(4-Benzylpiperidin-1-yl)-2-chloroethan-1-oneHCID 1129608—
SolventDiethyl EtherHCID 3283—
Product1-(4-Benzyl-piperidin-1-yl)-2-(1H-indazol-5-yl-amino)-ethanoneHCID 69100383—

Reaction Steps

The title compound is prepared from 5-aminoindazol and 2-chloro-1-(4-benzyl-piperidin-1-yl)-ethanone according to the method described in Example 142b. Melting Point: 153-155° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-1a670c8405664bc6b67b2edbd26d5f5c
Source noteuspto-grants-2008_10