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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115130Generated: October 25, 2026

Diethyl Ether → 2-(4-p-Tolyloxy-piperidin-1-yl)-2-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl-amino)-ethanone

https://huagongshe.com/reaction/2115130

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
Reactant7-amino-3,4-dihydro-2H-1,4-benzoxazin-3-oneHCID 2764182—
Reactant2-Chloro-1-(4-p-tolyloxy-piperidin-1-yl) ethanoneHCID 69100302—
Product2-(4-p-Tolyloxy-piperidin-1-yl)-2-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl-amino)-ethanoneHCID 86593934—

Reaction Steps

The title compound is prepared from 7-amino-4H-benzo[1,4]oxazin-3-one and 2-chloro-1-(4-p-tolyloxy-piperidin-1-yl) ethanone (Example 208a) according to the method described in Example 206. Melting Point: 223-224° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-d1e2f6f4283f47d4bbd295a663b9aa74
Source noteuspto-grants-2008_10