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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115131Generated: October 26, 2026

2(3H)-Benzothiazolone, 6-amino- → 1-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-(2-oxo-2,3-dihydro-benzothiazol-6-yl-amino)-ethanone

https://huagongshe.com/reaction/2115131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2(3H)-Benzothiazolone, 6-amino-HCID 6453329—
Reactant2-Chloro-1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanoneHCID 69100056—
SolventDiethyl EtherHCID 3283—
Product1-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-(2-oxo-2,3-dihydro-benzothiazol-6-yl-amino)-ethanoneHCID 69100048—

Reaction Steps

The title compound is prepared from 6-amino-3H-benzothiazol-2-one and 2-chloro-1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanone (Example 197a) according to the method described in Example 206. Melting Point: 149-155° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-991911cbfaef4c66b58f21183ae86377
Source noteuspto-grants-2008_10