HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Benzylpiperidin-1-yl)-2-chloroethan-1-one → 6-[2-(4-Benzyl-piperidin-1-yl)-2-oxo-ethylamino]-3,4-dihydro-1H-quinolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Benzylpiperidin-1-yl)-2-chloroethan-1-one | HCID 1129608 | — |
| Reactant | 6-amino-3,4-dihydroquinolin-2(1H)-one | HCID 4912759 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-[2-(4-Benzyl-piperidin-1-yl)-2-oxo-ethylamino]-3,4-dihydro-1H-quinolin-2-one | HCID 69100229 | — |
Reaction Steps
The title compound is prepared from 6-amino-3,4-dihydro-1H-quinoline-2-one and 2-chloro-1-(4-benzyl-piperidin-1-yl)-ethanone (Example 200a) according to the method described in Example 206. Melting Point: 184-187° C. (ethanol)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-671cf0695f374d9489128a9f690b7e87 |
| Source note | uspto-grants-2008_10 |