Trifluoroacetic acid → HCID 178513831, compound

HRID 2115260Notes

Reaction equation

HRID 2115260 reaction equation
C(OC([NH:8][C:9]1[CH:10]=[CH:11][C:12]([N:15]2[CH2:20][CH2:19][C:18]3=[C:21]([C:24]([NH2:26])=[O:25])[NH:22][N:23]=[C:17]3[CH2:16]2)=[N:13][CH:14]=1)=O)(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[NH2:8][C:9]1[CH:10]=[CH:11][C:12]([N:15]2[CH2:20][CH2:19][C:18]3=[C:21]([C:24]([NH2:26])=[O:25])[NH:22][N:23]=[C:17]3[CH2:16]2)=[N:13][CH:14]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 178452763HCID 178452763, compound

Product 1

HCID 178513831HCID 178513831, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The amine group of the 6-(5-tert-butoxycarbonylaminopyridin-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-3-carboxamide is deprotected in acid medium (trifluoroacetic acid in dichloromethane) and results in the obtaining of 6-(5-aminopyridin-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-3-carboxamide.

Workup

  1. customresults in the

Sources & evidence

ORD record
ord-7b9d021bd91b40a9b137735d473d0ff0
Source dataset
uspto-grants-2008_10
Patent number
US07435820B2

Reaction notes

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