2-(Ethylamino)ethanol → HCID 63680661, compound

HRID 2115401Notes

Reaction equation

[Br:1][CH2:2][C:3](Br)=[O:4].[CH2:6]([NH:8][CH2:9][CH2:10][OH:11])[CH3:7].C(C1C=CC(S(NC2C=CC(C)=CC=2)(=O)=O)=CC=1)(C)(C)C>>[Br:1][CH2:2][C:3]([N:8]([CH2:6][CH3:7])[CH2:9][CH2:10][OH:11])=[O:4]

Participants

Reactant 3

HCID 80722-(Ethylamino)ethanol

HCID 61147Bromoacetyl bromide

HCID 8310754-tert-Butyl-N-p-tolyl-benzenesulfonamide

Product 1

HCID 63680661HCID 63680661, compound

Procedure

prepared by reaction of 2-bromoacetyl bromide with N-ethyl-N-(2-hydroxy-ethyl)-amine and 4-tert-butyl-N-p-tolyl-benzenesulfonamide; in contrast to the general procedure the intermediate 2-bromo-N-ethyl-N-(2-hydroxy-ethyl)-acetamide was isolated before being used in the coupling with the potassium N-tolylsulfonamide.

Sources & evidence

ORD record: ord-fb2a3673bbf147b3a717b2e6e5f59273
Source dataset: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07435815B2

Reaction notes

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