p-Toluidine → N,N-Diethyl-2-[(2-methoxy-4-methyl-benzenesulfonyl)-p-tolyl-amino]-acetamide
Reaction equation
Br[CH2:2][C:3]([N:5]([CH2:8][CH3:9])[CH2:6][CH3:7])=[O:4].[NH2:10][C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1.[CH3:18][O:19][C:20]1[CH:25]=[C:24]([CH3:26])[CH:23]=[CH:22][C:21]=1[S:27](Cl)(=[O:29])=[O:28]>>[CH2:6]([N:5]([CH2:8][CH3:9])[C:3](=[O:4])[CH2:2][N:10]([S:27]([C:21]1[CH:22]=[CH:23][C:24]([CH3:26])=[CH:25][C:20]=1[O:19][CH3:18])(=[O:29])=[O:28])[C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1)[CH3:7]Participants
4
Procedure
prepared by reaction of 2-bromo-N,N-diethylacetamide with p-toluidine and 2-methoxy-4-methyl-benzenesulfonyl chloride
Sources & evidence
- ORD record
- ord-fd74aeac9601480b9908605b2f8b6f0d
- Source dataset
- uspto-grants-2008_10
- Patent number
- US07435815B2
Reaction notes
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