p-Toluidine → N,N-Diethyl-2-[p-tolyl-(3-trifluoromethyl-benzenesulfonyl)-amino]-acetamide
Reaction equation
Br[CH2:2][C:3]([N:5]([CH2:8][CH3:9])[CH2:6][CH3:7])=[O:4].[NH2:10][C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1.[F:18][C:19]([F:31])([F:30])[C:20]1[CH:21]=[C:22]([S:26](Cl)(=[O:28])=[O:27])[CH:23]=[CH:24][CH:25]=1>>[CH2:6]([N:5]([CH2:8][CH3:9])[C:3](=[O:4])[CH2:2][N:10]([C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1)[S:26]([C:22]1[CH:23]=[CH:24][CH:25]=[C:20]([C:19]([F:18])([F:30])[F:31])[CH:21]=1)(=[O:28])=[O:27])[CH3:7]Participants
4
Procedure
prepared by reaction of 2-bromo-N,N-diethylacetamide with p-toluidine and 3-trifluoromethyl-benzenesulfonyl chloride
Sources & evidence
- ORD record
- ord-6105ceb97b594346a45a09584f8d61dc
- Source dataset
- uspto-grants-2008_10
- Patent number
- US07435815B2
Reaction notes
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