Dichloromethane → 3-Fluoro-1,3′-biazetidine

HRID 211556Notes

Reaction equation

HRID 211556 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:12]2[CH2:13][CH:14]([F:16])[CH2:15]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:7].[Cl:17][CH2:18][Cl:19].[F:20][C:21]([F:22])([F:23])[C:24]([OH:25])=[O:26]>>[NH:8]1[CH2:9][CH:10]([N:12]2[CH2:13][CH:14]([F:16])[CH2:15]2)[CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59605557Tert-butyl 3-(3-fluoroazetidin-1-yl)azetidine-1-carboxylate

Product 1

HCID 596057843-Fluoro-1,3′-biazetidine

Sources & evidence

ORD record
ord-d941eb8e369e4032a23565d7e1f45ba6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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