1-Dodecanethiol → Sodium dodecane-1-thiolate

HRID 2115590Notes

Reaction equation

HRID 2115590 reaction equation
[CH2:1]([SH:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C[O-].[Na+:16]>CO>[CH2:1]([S-:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[Na+:16]

Participants

4

Reactant 2

HCID 81951-DodecanethiolHCID 10942334Sodium Methoxide

Product 1

HCID 23672953Sodium dodecane-1-thiolate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Dodecanethiol (246 g) and sodium methylate in methanol 30% (216 g) are charged to a rotary evaporator. Vacuum is applied and the solvent is abstracted completely using a bath temperature up to 90° C. The remaining sodium dodecanethiolate (272 g) is used without further purification in the subsequent step.

Workup

  1. customup to 90° C
  2. customThe remaining sodium dodecanethiolate (272 g) is used without further purification in the subsequent step

Sources & evidence

ORD record
ord-e065efd27bdc4ae29861cdebd52379cf
Source dataset
uspto-grants-2008_10
Patent number
US07435854B2

Reaction notes

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