Methylamine → HCID 69107859, compound

HRID 2116314Notes

Reaction equation

HRID 2116314 reaction equation
CC1C=CC(S(O[CH2:12][CH:13]2[CH2:17][C:16]3[CH:18]=[CH:19][CH:20]=[C:21]([C:22]4[CH:27]=[C:26]([CH3:28])[CH:25]=[CH:24][C:23]=4[CH3:29])[C:15]=3[O:14]2)(=O)=O)=CC=1.[CH3:30][NH2:31]>>[CH3:30][NH:31][CH2:12][CH:13]1[CH2:17][C:16]2[CH:18]=[CH:19][CH:20]=[C:21]([C:22]3[CH:27]=[C:26]([CH3:28])[CH:25]=[CH:24][C:23]=3[CH3:29])[C:15]=2[O:14]1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 86599150HCID 86599150, compound

Product 1

HCID 69107859HCID 69107859, compound

Procedure

The title compound was prepared (0.091 g, 65%) following the general procedure of Example 390 as a white solid, hydrochloride salt from (±)-[7-(2,5-dimethylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate (0.091 g, 0.22 mmol) and methylamine (0.069 g, 2.22 mmol). mp 186-189° C.

Sources & evidence

ORD record
ord-fd6b487bd0cb41129ee3f10d848fad2b
Source dataset
uspto-grants-2008_10
Patent number
US07435837B2

Reaction notes

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