Methylamine → HCID 68966956, compound

HRID 2116321Notes

Reaction equation

HRID 2116321 reaction equation
CC1C=CC(S(O[CH2:12][CH:13]2[CH2:17][C:16]3[CH:18]=[CH:19][CH:20]=[C:21]([C:22]4[CH:23]=[N:24][CH:25]=[CH:26][CH:27]=4)[C:15]=3[O:14]2)(=O)=O)=CC=1.[CH3:28][NH2:29]>>[CH3:28][NH:29][CH2:12][CH:13]1[CH2:17][C:16]2[CH:18]=[CH:19][CH:20]=[C:21]([C:22]3[CH:23]=[N:24][CH:25]=[CH:26][CH:27]=3)[C:15]=2[O:14]1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 86599293HCID 86599293, compound

Product 1

HCID 68966956HCID 68966956, compound

Procedure

The title compound was prepared (0.367 g, 70%) following the general procedure of Example 390 as a white solid, hydrochloride salt from (7-pyridin-3-yl-2,3-dihydro-1-benzofuran-2-yl)methyl 4-methylbenzenesulfonate (0.730 g, 1.91 mmol) and methylamine (1.14 g, 36.7 mmol). mp 212-215° C.

Sources & evidence

ORD record
ord-a1d40710c88d4e49abaac21b3718be6e
Source dataset
uspto-grants-2008_10
Patent number
US07435837B2

Reaction notes

Loading…