Methylamine → HCID 68964704, compound

HRID 2116385Notes

Reaction equation

HRID 2116385 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:16]2[O:15][CH:14]([CH2:17]OS(C3C=CC(C)=CC=3)(=O)=O)[CH2:13][C:12]=2[CH:11]=[C:10]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:9]=1.[CH3:35][NH2:36]>>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:16]2[O:15][CH:14]([CH2:17][NH:36][CH3:35])[CH2:13][C:12]=2[CH:11]=[C:10]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 86599350HCID 86599350, compound

Product 1

HCID 68964704HCID 68964704, compound

Procedure

The title compound was prepared (0.055 g, 70%) following the general procedure of Example 390 as a white solid, hydrochloride salt from (±)-{[7-(2-methylphenyl)-5-phenyl-2,3-dihydro-1-benzofuran-2-yl]methyl}4-methylbenzenesulfonate (0.10 g, 0.21 mmol) and methylamine (0.30 g, 9.8 mmol). mp 232-235° C.

Sources & evidence

ORD record
ord-8326e4161c1a4242893d4055b400baf8
Source dataset
uspto-grants-2008_10
Patent number
US07435837B2

Reaction notes

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