Methylamine → HCID 68966035, compound

HRID 2116393Notes

Reaction equation

HRID 2116393 reaction equation
CC1C=CC(S(O[CH2:12][CH:13]2[CH2:17][C:16]3[CH:18]=[C:19]([C:29]([F:32])([F:31])[F:30])[CH:20]=[C:21]([C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([CH3:28])[CH:23]=4)[C:15]=3[O:14]2)(=O)=O)=CC=1.[CH3:33][NH2:34]>>[CH3:33][NH:34][CH2:12][CH:13]1[CH2:17][C:16]2[CH:18]=[C:19]([C:29]([F:32])([F:31])[F:30])[CH:20]=[C:21]([C:22]3[CH:27]=[CH:26][CH:25]=[C:24]([CH3:28])[CH:23]=3)[C:15]=2[O:14]1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 86599358HCID 86599358, compound

Product 1

HCID 68966035HCID 68966035, compound

Procedure

The title compound was prepared (0.026 g, 67%) following the general procedure of Example 390 as a white solid, hydrochloride salt from [7-(3-methylphenyl)-5-(trifluoromethyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate (0.050 g, 0.11 mmol) and methylamine (0.12 g, 3.9 mmol). mp 228-230° C.

Sources & evidence

ORD record
ord-4a482953decc4dbda0053541b3bb3f3b
Source dataset
uspto-grants-2008_10
Patent number
US07435837B2

Reaction notes

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