HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2116455Generated: October 25, 2026
Sodium methanethiolate → N-(4-Chlorophenyl)-9-ethyl-2-(methylthio)-9H-purin-6-amine
https://huagongshe.com/reaction/2116455
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium methanethiolate | HCID 4378561 | — |
| Reactant | 2-Chloro-N-(4-chlorophenyl)-9-ethyl-9H-purin-6-amine | HCID 21988264 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | N-(4-Chlorophenyl)-9-ethyl-2-(methylthio)-9H-purin-6-amine | HCID 69215764 | — |
Reaction Steps
A mixture of the product from step (ii) (0.6 g) and sodium thiomethoxide (0.45 g) in dimethylsulphoxide (15 ml) was heated at 110° C. for 4 h. The mixture was partitioned between ethyl acetate and water, the organics washed with water, dried (MgSO4) and evaporated under reduced pressure. Yield 0.45 g
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07439240B2 |
|---|
| Source dataset | uspto-grants-2008_10 |
|---|
| ORD ID | ord-7f42dc0cfc5c4c3aafe0bafa0a95f05c |
|---|
| Source note | uspto-grants-2008_10 |
|---|
