Pyridine → HCID 59728304, compound

HRID 2116628Notes

Reaction equation

HRID 2116628 reaction equation
N1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:8][OH:9].O1[CH2:15][CH2:14]OCC1>>[CH2:2]1[C:15]2([CH2:14][CH2:5][CH2:4][CH2:3][CH2:2]2)[CH2:6][CH2:5][C:4](=[N:8][OH:9])[CH2:3]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 312751,4-DioxaneHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 59728304HCID 59728304, compound

Procedure

70 ml of pyridine and 3.45 g of hydroxylamine hydrochloride are added to 39 mmol of the compound obtained in the above Step in solution in dioxane. The reaction mixture is then heated at reflux overnight and subsequently concentrated to dryness to yield an oil, which crystallises and which is washed with water to yield the expected product in the form of a powder after filtration and drying.

Workup

  1. temperatureThe reaction mixture is then heated
  2. temperatureat reflux overnight
  3. concentrationsubsequently concentrated to dryness
  4. customto yield an oil, which
  5. customcrystallises
  6. washwhich is washed with water

Sources & evidence

ORD record
ord-d91a6c967c25439581c42f441012db21
Source dataset
uspto-grants-2008_10
Patent number
US07439263B2

Reaction notes

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