Triphenylphosphane dibromide → HCID 59814839, compound

Participants

Reaction Steps

4-(4-fluorophenyl)-7-hydroxy-8-methyl-2-H-chromen-2-one, (4.47 g, 16.5 mol) and triphenylphosphine dibromide (7.68 g, 18.2 mmol) were heated in a sand bath at 320-350° C. for 0.5 h. The cooled mixture was dissolved in dichloromethane, silica gel was added and the mixture was evaporated. Chromatography on silica gel (hexane/EtOAC; 90:10), gave the title compound.

Provenance & Evidence