Lauric Acid → 2,6-dimethyl-7a-undecyl-tetrahydro-2H-oxazolo[2,3-b]oxazole

Participants

Reaction Conditions

Reaction Steps

To a 1 liter stirred reactor, equipped with a distillation column, condenser, and graduated receiver, the following constituents were added: 166.5 g of diisopropanol amine (DIPA) and 200.0 9 (98%) of lauric acid. The contents were heated to 186° C. under a nitrogen blanket. After 111 minutes, 15 ml of water had come overhead. The batch temperature was allowed to drop to 172° C. while the pressure was dropped to 10,531 Pa. The batch temperature was then raised to 195° C. and the pressure was raised to 13,330 Pa. The batch temperature was slowly raised to 220° C. while the batch pressure was increased to 19,800 Pa. An additional 13 ml of a mixture of water and DIPA came overhead. The temperature was then allowed to drop to 182° C. while the pressure was dropped to 280 Pa. During the pressure reduction, 31.2 g of DIPA came overhead. As the pressure was dropped to 227 Pa and the temperature increased to 221° C., a total of 93.4 g of the amide acetal of lauric acid was collected.

Provenance & Evidence