Methyl Bromide → HCID 10136004, compound

HRID 2116874Notes

Reaction equation

[CH3:1][Br:2].[C:3]([N:7]([CH3:25])[CH2:8][CH2:9][C@@H:10]([C:17]1[CH:22]=[C:21]([CH3:23])[CH:20]=[CH:19][C:18]=1[OH:24])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)([CH3:6])([CH3:5])[CH3:4]>>[Br-:2].[C:3]([N+:7]([CH3:1])([CH3:25])[CH2:8][CH2:9][C@@H:10]([C:17]1[CH:22]=[C:21]([CH3:23])[CH:20]=[CH:19][C:18]=1[OH:24])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)([CH3:6])([CH3:5])[CH3:4]

Participants

Reactant 2

HCID 6323Methyl Bromide

HCID 69134093HCID 69134093, compound

Product 1

HCID 10136004HCID 10136004, compound

Procedure

Following the general procedure of Example 2 and making non critical variations, but starting with methyl bromide and 2-{(1R)-3-[tert-butyl(methyl)amino]-1-phenylpropyl}-4-methylphenol, the title compound is obtained.

Sources & evidence

ORD record: ord-45c467a6e88b423b97e27b5f05f3254f
Source dataset: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07439397B2

Reaction notes

Loading…