HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 86608238, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1-[(tert-Butoxycarbonyl)amino]-2,3-dihydro-1H-indene-1-carboxylic acid | HCID 2733195 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86608238 | HCID 86608238 | — |
Reaction Steps
To 0.140 mol of 1-[(tert-butyloxycarbonyl)amino]-1-indancarboxylic acid there are added 750 ml of dimethylformamide and then 0.147 mol of caesium carbonate. Stirring is then carried out for 2 hours 30 minutes at ambient temperature and there is then poured in, dropwise, over ½ hour, 0.145 mol of benzyl bromide dissolved in 150 ml of dimethyl-formamide, and stirring is carried out for 20 hours at ambient temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442692B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-18beb380a27e4a92bb0c8a78ee6d4925 |
| Source note | uspto-grants-2008_10 |