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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2117262Generated: October 30, 2026

Thionyl Chloride → 3,4-Difluorobenzenepropanoyl chloride

https://huagongshe.com/reaction/2117262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant3-(3,4-Difluorophenyl)prop-2-enoic acidHCID 145486—
CatalystDimethylformamideHCID 6228—
Solvent1,1-DichloroethaneHCID 6365—
Product3,4-Difluorobenzenepropanoyl chlorideHCID 57585975—

Reaction Steps

To 0.27 mol of 3,4-difluorocinnamic acid dissolved in dichloroethane there are added 20 drops of dimethylformamide and 100 ml of thionyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07442692B2
Source datasetuspto-grants-2008_10
ORD IDord-e7d404ec0d5e4f63875cfd8f341b6cf5
Source noteuspto-grants-2008_10