Ethyl Acrylate → HCID 86600603, compound

HRID 2117372Notes

Reaction equation

HRID 2117372 reaction equation
[Br-].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([C:13](=[O:21])[CH2:14][N+:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:7]=[CH:8][C:9]=1[N+:10]([O-:12])=[O:11].[C:22]([O:26][CH2:27][CH3:28])(=[O:25])[CH:23]=[CH2:24]>>[CH3:2][O:3][C:4]1[CH:5]=[C:6]([CH:7]=[CH:8][C:9]=1[N+:10]([O-:12])=[O:11])[C:13]([C:14]1[N:15]2[C:16]([CH:17]=[CH:18][CH:19]=[CH:20]2)=[C:23]([C:22]([O:26][CH2:27][CH3:28])=[O:25])[CH:24]=1)=[O:21]

Participants

3

Reactant 2

HCID 8821Ethyl AcrylateHCID 86600604HCID 86600604, compound

Product 1

HCID 86600603HCID 86600603, compound

Procedure

This compound is obtained according to the same method as the preceding example in Step B by 1,3-dipolar cycloaddition of 1-[2-(3-methoxy-4-nitrophenyl)-2-oxoethyl]pyridinium bromide (obtained in Step A of the preceding example) with ethyl acrylate. A yellow powder is obtained after purification by flash chromatography on a silica column, eluting with dichloromethane.

Workup

  1. customThis compound is obtained
  2. customA yellow powder is obtained
  3. customafter purification by flash chromatography on a silica column
  4. washeluting with dichloromethane

Sources & evidence

ORD record
ord-4db420707c424af4939d99b6cf07ba4c
Source dataset
uspto-grants-2008_10
Patent number
US07442708B2

Reaction notes

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