HCID 12069557, compound → HCID 12069578, compound

HRID 2117373Notes

Reaction equation

HRID 2117373 reaction equation
C([O:8][C:9]1[C:10]([CH3:31])=[C:11]([C:18]([C:20]2[CH:25]=[CH:24][C:23]([N+:26]([O-:28])=[O:27])=[C:22]([O:29][CH3:30])[CH:21]=2)=[O:19])[N:12]2[C:17]=1[CH:16]=[CH:15][CH:14]=[CH:13]2)C1C=CC=CC=1>FC(F)(F)C(O)=O>[OH:8][C:9]1[C:10]([CH3:31])=[C:11]([C:18]([C:20]2[CH:25]=[CH:24][C:23]([N+:26]([O-:28])=[O:27])=[C:22]([O:29][CH3:30])[CH:21]=2)=[O:19])[N:12]2[C:17]=1[CH:16]=[CH:15][CH:14]=[CH:13]2

Participants

3

Reactant 1

HCID 12069557HCID 12069557, compound

Product 1

HCID 12069578HCID 12069578, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

A solution of 5 g (12 mmol) of [1-(benzyloxy-2-methylindolizin-3-yl](3-methoxy-4-nitrophenyl)methanone, a compound of Example 3, in 30 ml of trifluoroacetic acid, is heated under reflux for 2 hours.

Workup

  1. temperatureunder reflux for 2 hours

Sources & evidence

ORD record
ord-08d03665a3a94ec18b4116beebec4c7f
Source dataset
uspto-grants-2008_10
Patent number
US07442708B2

Reaction notes

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